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Differential Expression of Adenosine A3 Receptors Controls Adenosine A2A Receptor-Mediated Inhibition of TLR Responses in Microglia
Journal of Immunology, 06/09/09
Putten CVD et al. - The authors report a differential, activation state-specific expression of ADORA in microglia and uncover a role for A3R as dynamically regulated suppressors of A2AR-mediated inhibition of TLR-induced responses. This would suggest exploration of combinations of A2AR agonists and A3R antagonists to dampen microglial activation during chronic neuroinflammatory conditions.
Today in Neurologic/Ophthalmic...keeping you current
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Evidence of STAT5-dependent and -independent routes to CD8 memory formation and a preferential role for IL-7 over IL-15 in STAT5 activation
Immunology & Cell Biology, 12/08/09
The effects of bilastine compared with cetirizine, fexofenadine, and placebo on allergen-induced nasal and ocular symptoms in patients exposed to aeroallergen in the Vienna Challenge Chamber
Inflammation Research, 12/07/09
Th1, Th17, and Th9 Effector Cells Induce Experimental Autoimmune Encephalomyelitis with Different Pathological Phenotypes
Journal of Immunology, 12/07/09
Today in Rheumatic/Autoimmune...keeping you current
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Potential role of interleukin-17 in the pathogenesis of bullous pemphigoid
Medical Hypotheses, 12/08/09
Crystal-induced neutrophil activation
Immunology & Cell Biology, 12/08/09
Inhibition of clonal expansion by Foxp3 expression as a mechanism of controlled T-cell responses and autoimmune disease
European Journal of Immunology, 12/07/09
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