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Seroprevalence and Placental Transportation of Maternal Antibodies Specific for Neisseria meningitidis Serogroup C, Haemophilus influenzae Type B, Diphtheria, Tetanus, and Pertussis
Clinical Infectious Diseases, 06/02/09

De Voer RM et al. - Antibody concentrations directed toward polysaccharide were equal in maternal and cord blood, whereas antibody concentrations to proteins were 1.6 times higher in cord blood than in maternal blood. This is probably attributable to the less-active transportation of immunoglobulin G2 antibodies elicited by polysaccharide. Despite proper placental transfer, cord antibody concentrations are low, possibly placing neonates at risk before they receive their primary vaccinations.

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