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Vasdev N et al. - The autoimmune clinical manifestations associated with intravesical BCG and INF-alpha2b are often acute in onset following intravesical installation. Serum acute phase reactants are commonly elevated during the onset of symptoms. The data suggests that pre-instillation prophylactic anti-inflammatory therapy may be useful in prevention of autoimmune clinical manifestation following BCG +- INF-alpha2b intravesical immunotherapy.

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