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Osteoclasts and the immune system
Journal of Bone and Mineral Metabolism, 06/04/09
Nakashima T et al. - Here the authors describe the efforts to address the challenging question as to how abnormal T-cell activation mechanistically induces bone destruction. The scope of osteoimmunology has been extended to encompass a wide range of molecular and cellular interactions, the elucidation of which will provide a scientific basis for future therapeutic approaches to diseases related to both the bone and immune systems.
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Bim-Mediated Apoptosis Is Not Necessary for Thymic Negative Selection to Ubiquitous Self-Antigens
Journal of Immunology, 12/11/09
Control of central self-tolerance induction by autoreactive CD4+ thymocytes
Trends in Immunology, 12/10/09
Autoimmune Regulator Deficiency Results in Decreased Expression of CCR4 and CCR7 Ligands and in Delayed Migration of CD4+ Thymocytes
Journal of Immunology, 12/10/09
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