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See Latest ArticlesZidovudine, Lamivudine, and Nelfinavir Concentrations in Amniotic Fluid and Maternal Serum
HIV Clinical Trials, 04/17/09
Bennetto-Hood C et al. - NFV and M8 exhibited partial drug transfer and/or accumulation in the amniotic compartment, whereas ZDV and 3TC concentrations mostly exceeded that in maternal plasma. Overall, all drugs achieved exposures in the amniotic fluid in excess of their wild-type viral susceptibilities. Amniotic fluid is an important compartment in the prevention of mother-to-child transmission.
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