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Evolution of hepatitis C virus hypervariable region 1 in immunocompetent children born to HCV-infected mothers
Journal of Viral Hepatitis, 04/07/09
Gismondi MI et al. - The data suggest peculiar evolutionary dynamics in these patients, which could be attributed to a mechanism of nucleotide invariability along with purifying selection operating on the HVR1. The lack of HVR1 variability may reflect the adaptation of the virus to a particular environment within each patient or a phenomenon of immune tolerance generated in these immunocompetent patients earlier in life.
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Why are some children with early onset of asthma getting better over the years? - Diagnostic failure or salutogenetic factors
International Journal of Medical Sciences , 12/04/09
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