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Immune modulation in type 1 diabetes mellitus using DiaPep277: a short review and update of recent clinical trial results
Diabetes/Metabolism Research and Reviews, 03/10/09
Eldor R et al. - A combined analysis of all the adult phase II studies revealed that DiaPep277 significantly inhibits the decline in stimulated C-peptide secretion (thus preserving endogenous insulin secretion). This effect was more pronounced in patients with a high beta-cell reserve at the start of the treatment. Furthermore, opposite trends in glycemic control of DiaPep277 treated patients where noted as opposed to placebo treated patients.
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Bim-Mediated Apoptosis Is Not Necessary for Thymic Negative Selection to Ubiquitous Self-Antigens
Journal of Immunology, 12/11/09
Control of central self-tolerance induction by autoreactive CD4+ thymocytes
Trends in Immunology, 12/10/09
Autoimmune Regulator Deficiency Results in Decreased Expression of CCR4 and CCR7 Ligands and in Delayed Migration of CD4+ Thymocytes
Journal of Immunology, 12/10/09
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