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Effects of type I interferons on IGF-mediated autocrine/paracrine growth of human neuroendocrine tumor cells
Endocrinology and Metabolism, 03/03/09
Vitale G et al. - The data demonstrate that the IGF system has an important role in autocrine/paracrine growth of BON cells. The more potent antitumor activity of IFN-beta compared with IFN- could be explained by several effects on this system: both IFNs inhibit the transcription of IGF-II, but the suppression is significantly higher after IFN-beta than IFN- and only IFN-beta inhibits the expression of IGF-I receptor.
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Bim-Mediated Apoptosis Is Not Necessary for Thymic Negative Selection to Ubiquitous Self-Antigens
Journal of Immunology, 12/11/09
Control of central self-tolerance induction by autoreactive CD4+ thymocytes
Trends in Immunology, 12/10/09
Autoimmune Regulator Deficiency Results in Decreased Expression of CCR4 and CCR7 Ligands and in Delayed Migration of CD4+ Thymocytes
Journal of Immunology, 12/10/09
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