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Human dendritic cells transfected with allergen-DNA stimulate specific immunoglobulin G4 but not specific immunoglobulin E production of autologous B cells from atopic individuals in vitro
Immunology, 10/29/07
Konig, B., et al. - Atopic/allergic diseases are characterized by T helper 2 (Th2)-dominated immune responses resulting in immunoglobulin E (IgE) production. DNA-based immunotherapies have been shown to shift the immune response towards Th1 in animal models. In further studies we showed that human dendritic cells (DC) transfected with allergen-DNA are able to stimulate autologous CD4+ T cells from atopic individuals to produce Th1 instead of Th2 cytokines and to activate interferon-gamma (IFN-gamma)-producing CD8+ T cells
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Good agreement between parental and self-completed questionnaires about allergic diseases and environmental factors in teenagers
Journal of Clinical Epidemiology, 12/11/09
Effects of omalizumab on basophil and mast cell responses using an intranasal cat allergen challenge
Journal of Allergy and Clinical Immunology, 12/10/09
Early-life EBV infection protects against persistent IgE sensitization
Journal of Allergy and Clinical Immunology, 12/10/09
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