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Induction of Transplantation Tolerance via Regulatory T Cells
Inflammation & Allergy - Drug Targets, 10/31/06
Battaglia, Manuela, et al. - In the last two decades, graft survival has been greatly improved by the introduction of efficient immunosuppressive drugs. On the other hand, late graft loss caused by chronic rejection together with the side effects of long-term immunosuppression, remain major obstacles for successful transplantation...This review attempts to summarize the most novel and successful strategies to achieve operational tolerance via induction of Tregs
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