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Modeling of tumor necrosis factor receptor superfamily 1A mutants associated with tumor necrosis factor receptor-associated periodic syndrome indicates misfolding consistent with abnormal function
Arthritis & Rheumatism, 09/01/06
Susana L. Rebelo, et al. - To investigate the effect of mutations in the tumor necrosis factor receptor superfamily 1A (TNFRSF1A) gene on the conformation and behavior of the TNFRSF1A protein...Conclusion: The results obtained from the in vitro experiments, in combination with the modeled structures, indicate that the phenotype and clinical differences between different TRAPS-associated mutants of TNFRSF1A result from different conformations of the TNFRSF1A ectodomains
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Alanine mutagenesis of the primary antigenic escape residue cluster (C1) of Apical Membrane Antigen-1
Infection and Immunity, 12/08/09
Role of RpoS in virulence of pathogens
Infection and Immunity, 12/08/09
The antimicrobial activity of CCL28 is dependent on C-terminal positively-charged amino acids
European Journal of Immunology, 12/08/09
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