Peripheral Blood NK Cell Cytotoxicities are Negatively Correlated with CD8sup+/sup T Cells in Fertile Women but not in Women with a History of Recurrent Pregnancy Loss

American Journal of Reproductive Immunology, 06/08/2012

NK cell–mediated immunopathology plays a role in recurrent pregnancy loss (RPL). Women with RPL have a disrupted immune regulation between cytotoxic T and NK cells. Failure of immune modulation by CD8+ T cells may exert NK cell activation and reproductive failures in women with RPL.

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