Anti-inflammatory effects of high-dose IgG on TNF--activated human coronary artery endothelial cells

European Journal of Immunology, 05/15/2012

The findings suggest that the clinical effects of infusion of IgG (IVIG) on Kawasaki disease (KD) patients are at least in part due to its direct anti–inflammatory effects on the coronary endothelium, which is a major lesion site in the pathogenesis of KD.

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