Foxp3+Treg cells in the inflamed CNS are insensitive to IL-6-driven IL-17 production

European Journal of Immunology, 05/11/2012

The authors propose that extinguished responsiveness to IL–6 (via down–regulation of CD126 and gp130) stabilizes the regulatory phenotype of activated T regulatory (Treg) cells at sites of autoimmune inflammation.

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