The lowest X4 Geno2Pheno false positive rate is associated with greater CD4-depletion in HIV-1 infected patients

Clinical Microbiology and Infection, 05/09/2012

In conclusion, these findings show that within the context of genotypically–assessed CXCR4 tropism, FPR ≤2% defines (far better than 10%–FPR) a viral population associated with low CD4–rank, with potentially greater cytopathic effect, and with more advanced disease.

Print Article Summary Cat 2 CME Report