Preventive immunization of aged and juvenile non-human primates to beta-amyloid
Journal of Neuroinflammation, 05/04/2012Kofler J et al.
The results indicate that preventive Abeta immunization is a safe therapeutic approach lacking adverse CNS immune system activation or other serious side–effects in both aged and juvenile NHP cohorts. A significant shift in the composition of soluble oligomers towards smaller species might facilitate removal of toxic Abeta species from the brain.
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