Isolation of filamentous fungi from sputum in asthma is associated with reduced post-bronchodilator FEV1.
Clinical & Experimental Allergy, 04/27/2012Agbetile J et al.
Numerous thermotolerant fungi other than A. fumigatus can be cultured from sputum of people with moderate–to–severe asthma; a positive culture is associated with an impaired post–bronchodilator FEV1, which might be partly responsible for the development of fixed airflow obstruction in asthma. Sensitization to these fungi is also common.
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