The premenstrual syndrome and fibromyalgia-similarities and common features
Amital D et al. - In this study, patients with premenstrual dysphoric syndrome (PMDD) were found to have higher levels of tenderness, higher psychiatric comorbidity, greater level of physical disabilities, and a lower quality of life. These parameters were highly correlated with a lower pain threshold. Methods- Aim was to assess the clinical similarities and common features of fibromyalgia syndrome (FM) and PMDD
- 30 young pts were compared to 26 women belonging to the medical staff of a general psychiatry department
- All enrollees were interviewed and examined by a skilled physician
- They completed the following nine survey items:
- demographic information, clinical health assessment questionnaire,
- fibromyalgia impact questionnaire, sleep and fatigue questionnaires,
- Sheehan disability scales, SF-36 assessment for QoL, VAS for pain,
- Mini International Neuropsychiatric Interview (MINI) questionnaire, and
- premenstrual severity scale
- Additionally, each isubject underwent a physical examination measuring the classical tender points
- They were asked to describe the distribution and continuum of pain or tenderness.
Results- PMDD group scored higher in pain, tenderness and in severity of premenstrual symptoms vs controls
- 5 pts in PMDD group had FM vs none in control
- QoL measured by SF-36 was higher in the control group vs PMDD group and correlated with the degree of tenderness reported
- Psychiatric comorbidity was more common in PMDD group, affecting 16 of 30 PMDD pts vs only 3 of 26 control pts
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