Activation of nitric oxide signaling by the rheumatoid arthritis shared epitope Song Ling, et al. - Susceptibility to rheumatoid arthritis (RA) is closely associated with HLA-DRB1 alleles encoding a shared epitope (SE) in positions 70-74 of the HLA-DRbeta chain...Conclusion: The SE can trigger NO-mediated signaling events in opposite cells, and may thereby contribute to RA pathogenesis [more...]
