Top beta 2 Articles in Allergy/Immunology

The effects of glucagon-like peptide-1 on the beta cell
Diabetes, Obesity and Metabolism, 11/06/2009

Vilsboll T – Preclinical studies have shown that both liraglutide and exenatide treatment can increase beta–cell mass, stimulate beta–cell proliferation, increase beta–cell neogenesis and inhibit beta–cell apoptosis. Clinical ... these findings in humans. Replication of these data in humans could have important clinical implications for the treatment of type 2 diabetes. [more...]

Polymorphism of the ADRB2 Gene and Response to Inhaled Beta- agonists in Children with Asthma: A Meta-analysis
Journal of Asthma, 11/10/2009

Finkelstein Y et al. – Failure of bronchodilator response to inhaled beta–agonists in asthmatic children is associated with the Gly allele (Arg/Gly and Gly/Gly genotypes) at position 16 of the beta–2&ndash ... receptor. Genetic typing for beta–2AR polymorphism may help identify children with drug–resistant asthma. [more...]

Synergistic effect of TGF-[beta] superfamily members on the induction of Foxp3+ Treg
European Journal of Immunology, 12/08/2009

Lu L et al. – Data further advocate that TGF–[beta] is a key signaling factor for Foxp3+ Treg development. In addition, the synergistic effect of BMP–2/4 and TGF–[beta] indicates that the simultaneous ... TGF–[beta] and BMP signaling might have considerable effects in the clinical setting for the enhancement of Treg purity and yield. [more...]

Beta-2 agonists in sport. Are the Anti-Doping rules meeting the needs of asthmatic athletes?
British Journal of Sports Medicine, 12/16/2009

Orellana JN et al. – The anti–doping regulations with respect to beta–2 agonists need to be reviewed and measures should be adopted to include a fall of 70% in FEV1% as an obstruction ... criterion to indicate a bronchodilation test and to extend the criterion for a positive methacholine test to a PC20 of 8 mg/ml. [more...]

Gene variants in the novel type 2 diabetes loci CDC123/CAMK1D, THADA, ADAMTS9, BCL11A and MTNR1B affect different aspects of pancreatic beta cell function
Diabetes, 11/05/2009

Simonis–Bik AM et al. – Diabetes risk alleles in CDC123/CAMK1D, THADA, ADAMTS9, BCL11A and MTNR1B are associated with various specific aspects of beta cell ... function. These findings point to a clear diversity in the impact that these different gene variants may have on (dys–)function of pancreatic beta cells. [more...]

Characterization of plasmids encoding CMY-2 AmpC beta-lactamases from Escherichia coli in Canadian intensive care units
Diagnostic Microbiology and Infectious Disease, 11/25/2009

Baudry PJ et al. – The dissemination of CMY–2 AmpC beta–lactamases among Escherichia coli in Canadian intensive care units occurs through a combination of [more...]

Defective Formation of the Inner Limiting Membrane In The Laminin beta 2 and delta 3 Null Retina Results in Retinal Dysplasia
Investigative Ophthalmology and Visual Science, 12/03/2009

Pinzon–Duarte GA et al. – These data suggest that beta 2 and delta 3 laminin isoforms are critical for the formation and stability of the ILM. These data also [more...]

Beta-2 adrenergic receptor gene polymorphisms Gln27Glu, Arg16Gly in patients with heart failure
BMC Cardiovascular Disorders, 11/04/2009

Mansur AJ et al. – In this study sample, the authors were not able to demonstrate an overall influence of polymorphisms Gln27Glu and Arg16Gly of beta–2 receptor gene on prognosis [more...]

Evasion of the Mucosal Innate Immune System by Herpes Simplex Virus Type 2
Journal of Virology, 11/12/2009

Peng T et al. – The findings of extremely low levels of IFN–alpha and IFN–beta, despite the presence of a large number of cells capable of synthesizing these substances, suggest a potent alteration in host defense during HSV–2 infection in vivo. HSV–2's [more...]

Anti-[beta]2 glycoprotein-I antibody increases the risk of pregnancy-induced hypertension: a case-controlled study
Journal of Reproductive Immunology, 12/07/2009

Yamada H et al. – This finding supports the utility of anti–[beta]2GPI determination as one of the laboratory criteria for anti–phospholipid syndrome classification ... usefulness of anti–[beta]2GPI measurement among women without other anti–phospholipid antibodies requires further study. [more...]