Peri-operative management of a patient with hereditary angioedema undergoing laparoscopic cholecystectomy
Anaesthesia, 12/08/2009
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Spyridonidou A et al. – Hereditary angioedema is a rare genetic disorder resulting from an inherited deficiency or dysfunction of the C1–esterase inhibitor of the classic ... operative care of a woman with hereditary angioedema undergoing laparoscopic cholecystectomy with emphasis on the role of anaesthetists as peri–operative physicians.
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Anaphylaxis and angioedema
Dermatology in Practice, 10/09/2009
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Anaphylaxis represents the most severe form of immediate allergic reaction and is due to the presence of immunoglobulin E (IgE) antibodies (type I hypersensitivity). Angioedema refers to localised deep tissue swelling and can occur as part of an anaphylactic reaction ... immunology,dermatopathology,dermatology
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Efficacy of human C1 esterase inhibitor concentrate compared with placebo in acute hereditary angioedema attacks
Journal of Allergy and Clinical Immunology, 09/25/2009
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Craig TJ et al. – C1 esterase inhibitor concentrate given intravenously at a dose of 20 U/kg is an effective and safe treatment for acute abdominal and facial attacks in patients with hereditary angioedema, with a rapid onset of relief ... immunology,dermatology,clinical pharmacology,critical care/emergency
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Possible montelukast-induced angioedema
American Journal of Health-System Pharmacy, 09/30/2009
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Sabbagh R et al. – A patient developed angioedema four times during one month of treatment with montelukast.
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Novel pathogenic mechanism and therapeutic approaches to angioedema associated with C1 inhibitor deficiency
Journal of Allergy and Clinical Immunology, 10/07/2009
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Bossi F et al. – The data suggest that both B1 receptor and gC1q receptor are involved in the vascular leakage induced by hereditary and acquired angioedema plasma.
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Human C1-Esterase Inhibitor Concentrate (Berinert(R))
BioDrugs, 11/10/2009
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is derived from human plasma and is indicated for the treatment of acute episodes of hereditary angioedema. Intravenous C1–INH concentrate was well tolerated in patients with hereditary angioedema, with no confirmed cases of viral transmission.
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Pathogenesis and laboratory diagnosis of hereditary angioedema
Allergy and Asthma Proceedings, 10/09/2009
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Zuraw BL et al. – The knowledge gained concerning the underlying mechanisms of the different types of HAE allow the clinician to approach the laboratory diagnosis with confidence and provides opportunities for novel therapeutic ... immunology,dermatology,diagnostics/radiology,radiology/diagnostics
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Supraglottic swelling may not correlate with tongue swelling in angiotensin converting enzyme inhibitor-induced angioedema
The Laryngoscope, 11/06/2009
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Saxena S et al. – The authors present a representative case. This observation suggests that all patients with ACEI–induced angioedema should undergo laryngeal fiberoptic examination and appropriate airway
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Frequency, timing, and type of prodromal symptoms associated with hereditary angioedema attacks
Allergy and Asthma Proceedings, 10/14/2009
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Prematta MJ et al. – Prodromes occur frequently before HAE attacks. This high frequency suggests that prodromal symptoms could be a reliable indication to begin treatment to prevent an acute HAE ... derm allergy/immunology
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Update on therapeutic developments for hereditary angioedema
Allergy and Asthma Proceedings, 10/12/2009
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Christiansen SC et al. – Potential options for the acute treatment of HAE will be discussed including purified C1INH, recombinant C1INH, an inhibitor of plasma kallikrein, and a B2–receptor antagonist. The arrival of these ... management of HAE.
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