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See Latest ArticlesFDA gives nod to new combination therapy for hypertension
Internet Source, 09/23/09
The study researchers compared the effects on BP of 150 mg and 300 mg doses of aliskiren and 160 mg and 320 mg doses of valsartan alone and in combination. The doses were increased to 300 mg of aliskiren and 320 mg of valsartan at four weeks. They reported that the combination aliskiren and valsartan reduced BP to a greater extent than the monotherapies alone or placebo. The mean reductions in mean systolic and diastolic BP from baseline were 17.2/12.2 mm Hg for the combination of aliskiren 300 mg and valsartan 320 mg, compared with 12.8/9.7 mm Hg for valsartan 320 mg alone, 13.0/9.0 mm Hg for aliskiren 300 mg alone and 4.6/4.1 mm Hg for placebo.
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