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Biomarkers as tools for improved diagnostic and therapeutic monitoring in SLE
Arthritis Research & Therapy, 11/25/09
Smith MF et al. – One of the major challenges in rheumatology is to overcome the classification criteria that previously defined SLE since the heterogeneity of the disease(s) appears to represent a complexity that likely substantially contributed to the failure of a number of recent trials. Use of validated patient stratification biomarkers possibly in conjunction with autoantibody profiles and disease manifestations will result in the recruitment of more homogenous patient populations during later stage clinical studies thereby decreasing size, costs, and risks in pivotal studies.
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Today in Diagnostics/Radiology...keeping you current
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An open-label pilot study evaluating by magnetic resonance imaging the potential for a disease-modifying effect of celecoxib compared to a modelized historical control cohort in the treatment of knee osteoarthritis
Seminars in Arthritis and Rheumatism, 02/09/10
Imaging the joint in osteoarthritis: a place for ultrasound
Best Practice & Research: Clinical Rheumatology, 02/03/10
Ultrasonography in Chondrocalcinosis
Joint, Bone, Spine, 01/29/10
Today in Systemic Lupus (SLE)...keeping you current
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Genetic variants and disease-associated factors contribute to enhanced interferon regulatory factor 5 expression in blood cells of patients with systemic lupus erythematosus
Arthritis & Rheumatism, 02/08/10
Expression of High Mobility Group Box Chromosomal Protein 1 and Its Modulating Effects on Downstream Cytokines in Systemic Lupus Erythematosus
Journal of Rheumatology, 02/03/10
Age at time of corticosteroid administration is a risk factor for osteonecrosis in pediatric patients with systemic lupus erythematosus: A prospective magnetic resonance imaging study
Arthritis & Rheumatism, 02/02/10
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