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Plasma level of myeloperoxidase in children with juvenile idiopathic arthritis (a pilot study)
Central European Journal of Medicine, 11/25/09
Pruunsild C et al. – Different subtypes of JIA may have different MPO-related backgrounds. MPO is a new potent inflammatory marker. Patients with polyarthritis have higher mean plasma MPO levels than patients with oligoarthritis and may therefore have an enhanced risk for subclinical oxidative stress-related atherogenic promotion
Methods- 38 JIA patients (25 girls and 13 boys) aged 9.1–11.8 years and 23 healthy controls (8 girls and 15 boys) participated
- 21 patients had oligoarthritis (8 with extended oligoarthritis) and 17 had polyarthritis (among them three were seropositive)
- Plasma concentration of MPO measured by ELISA technique
- Mean plasma concentration of MPO in JIA group significantly higher than in control group
- Patients with polyarthritis presented significantly higher mean plasma MPO level than patients with oligoarthritis
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