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See Latest ArticlesCorrelation of ESR, C3, C4, anti-DNA and lupus activity based on British Isles Lupus Assessment Group Index in patients of rheumatology clinic
Rheumatology International, 10/09/09
Nasiri AS et al. – This study aimed to determine the correlation between of ESR, C3, C4, anti-DNA, and lupus activity and also the construct and criterion validity of the British Isles Lupus Assessment Group (BILAG) index for assessing disease activity in systemic lupus erythematosus (SLE).The findings show that the ESR, C3, C4, and anti-DNA should be used in the evaluation and management of patients with SLE. Also the results show that the BILAG index has construct validity.
Methods- Patients with SLE recruited into cross-sectional study
- Data analyzed for estimating of SLE disease activity [scores on the BILAG index and Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2K)]
- Overall BILAG scores determined by highest score achieved in any of the individual systems in respective index
- ESR, C3 levels, C4 levels, anti-dsDNA levels, and SLEDAI-2K scores used in analysis of construct validity
- Statistical analyses performed using ordinal logistic regression for construct validity
- Of 100 patients with SLE, 90% women. Their mean ± SD age was 31.1 ± 9.8 years
- Increasing overall scores on the BILAG index associated with increasing ESRs, decreasing C3 levels, decreasing C4 levels, elevated anti-dsDNA levels, and increasing SLEDAI-2K scores
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Estimation of monocyte-chemoattractantprotein-1 (Mcp-1) level in patients with lupus nephritis
International Journal of Rheumatic Diseases, 11/25/09
Analysis of correlations between selected endothelial cell activation markers, disease activity, and nailfold capillaroscopy microvascular changes in SLE patients
Clinical Rheumatology, 11/17/09
Distinct subtypes of myelitis in systemic lupus erythematosus
Arthritis & Rheumatism, 11/06/09
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