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Article Summary

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Risk of development of lung cancer is increased in patients with rheumatoid arthritis: A large case control study in US veterans
Journal of Rheumatology, 07/21/08
Print     Email This Article     Save in My Library   Free Abstract
Khurana R et al. – These results shows a significant positive association between RA and the development of lung cancer in the veteran population. Veterans with RA have an increased incidence of lung cancer when compared to the non-RA population.

Methods
  • Study to investigate the occurrence of lung cancer in pts with RA in the US veteran population (n=483,721)
  • Pts were identified by searching for the diagnoses of RA and lung cancer based on the ICD codes
  • 8768 (1.81%) pts with a diagnosis of RA, 7280 (1.5%) pts with lung cancer, 247 pts with lung cancer and RA, and 7033 pts with lung cancer but no RA were identified
  • Logistic regression analysis was performed to adjust for age, gender, race, and tobacco and asbestos exposure

Results
  • The diagnosis of RA was determined to have a significant association with lung cancer in this veteran population
  • Pts with RA were 43% more likely to develop lung cancer than pts w/o RA, when adjusted for covariates

 

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