European League Against Rheumatism/European Vasculitis Study Group recommendations for the management of vasculitis
Current Opinion in Rheumatology, 10/16/2009
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Villa–Forte A – The purpose of formulating clinical recommendations is to improve quality of care and guide the clinician inexperienced with vasculitis. Nevertheless, patients with vasculitis should be ... vasculitis expert whenever possible. As the understanding of this rare and complex group of diseases advances, novel therapeutic options are being developed.
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Resolution of anti-neutrophil cytoplasmic antibody-associated vasculitis after resection of gastric cancer
Modern Rheumatology, 10/19/2009
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Hosoya Y et al. – Although ANCA–associated vasculitis occasionally accompanies malignant tumors, this is the first documented case of concurrent gastric cancer–associated and ANCA–associated vasculitis, with post&ndash ... resolution of the vasculitis.
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Progress Towards a Core Set of Outcome Measures in Small-vessel Vasculitis. Report from OMERACT 9
Journal of Rheumatology, 10/20/2009
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Merkel PA et al. – The focus of the OMERACT group to date has been on outcome measures in small–vessel vasculitis with an overall goal of creating a core set of outcome measures for vasculitis, each of which fulfills the ... process has been informed by several ongoing projects providing data on outcomes of disease activity, disease–related damage, multidimensional health–related quality of life, and patient–reported ratings of the burden of vasculitis.
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Cutaneous vasculitis induced by TNF inhibitors: a report of three cases
Modern Rheumatology, 10/16/2009
Fujikawa K et al. – We describe 3 rheumatoid arthritis (RA) patients with anti-tumor necrosis factor (TNF) therapy-induced cutaneous vasculitis. Two patients required oral corticosteroid, the efficacy of which was observed to ... cutaneous vasculitis2 cases induced by infliximab3rd case (cutaneous vasculitis found early at start of therapy) induced by etanerceptSkin biopsy obtained in 2 patientsResults- Histology-proven leukocytoclastic vasculitis in 2 patients
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Analysis of T-cell receptor usage in myeloperoxidase-antineutrophil cytoplasmic antibody-associated renal vasculitis
Clinical and Experimental Nephrology, 10/09/2009
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Hirayama K et al. – There was no difference in bacterial superantigens between controls and MPO–ANCA–associated vasculitis patients because of the absence of specific usage of TCR–V[beta ... rather than superantigens may be associated with the pathogenesis of MPO–ANCA–associated vasculitis.
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Mechanisms and markers of vascular damage in ANCA-associated vasculitis
Autoimmunity, 10/05/2009
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Haubitz M et al. – Such effects may well contribute to a pro–inflammatory environment in ANCA–associated small–vessel vasculitis and in vascular disease in general. Here, the authors review mechanisms ... associated vasculitis and put these findings into perspective.
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Small vessel vasculitis
Pediatric Nephrology, 11/11/2009
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Brogan P et al. – Significant challenges remain in the field of pediatric small vessel vasculitis, including the development of validated disease outcome measures and biomarkers to be used in clinical trials. Lastly, long–term outcome data are lacking in ... pediatric small vessel vasculitis.
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Antineutrophil Cytoplasmic Antibody-Associated Vasculitis Complicated With Diffuse Alveolar Hemorrhage: A Study of 12 Cases
Journal of Clinical Rheumatology (JCR), 10/12/2009
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Lin Y et al. – DAH is the most serious complication of ANCA–associated vasculitis. The episode of DAH always occurs simultaneously with multiple system ... dyspnea and new infiltration of bilateral lungs. Prompt bronchoalveolar lavage can be helpful for timely diagnosis of the patients without overt hemoptysis and a useful tool to exclude pulmonary infection.
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Ciprofloxacin-Induced Hemorrhagic Vasculitis
Annals of Vascular Surgery, 11/09/2009
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Berg FPVD et al. – Ciprofloxacin is among the standard treatments for infected ischemic ulcers; in the rare case of ciprofloxacin–induced hemorrhagic vasculitis, it might be interpreted as progression of infection, instead of a complication ... faulty diagnosis and treatment. The intention of this case report is to raise awareness for anyone prescribing ciprofloxacin as treatment for infected diabetic and ischemic ulcers.
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Update in paediatric vasculitis
Best Practice & Research: Clinical Rheumatology, 10/27/2009
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Ozen S et al. – This review concentrates on recent changes proposed for the classification of paediatric vasculitis and advances in the concepts of aetiopathogenesis. Availability of improved classification criteria for children should prompt planning for ... controlled studies for the treatment of these rare but important diseases.
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