Top vasculitis Articles in Rheumatology

European League Against Rheumatism/European Vasculitis Study Group recommendations for the management of vasculitis
Current Opinion in Rheumatology, 10/16/2009

Villa–Forte A – The purpose of formulating clinical recommendations is to improve quality of care and guide the clinician inexperienced with vasculitis. Nevertheless, patients with vasculitis should be ... vasculitis expert whenever possible. As the understanding of this rare and complex group of diseases advances, novel therapeutic options are being developed. [more...]

Resolution of anti-neutrophil cytoplasmic antibody-associated vasculitis after resection of gastric cancer
Modern Rheumatology, 10/19/2009

Hosoya Y et al. – Although ANCA–associated vasculitis occasionally accompanies malignant tumors, this is the first documented case of concurrent gastric cancer–associated and ANCA–associated vasculitis, with post&ndash ... resolution of the vasculitis. [more...]

Progress Towards a Core Set of Outcome Measures in Small-vessel Vasculitis. Report from OMERACT 9
Journal of Rheumatology, 10/20/2009

Merkel PA et al. – The focus of the OMERACT group to date has been on outcome measures in small–vessel vasculitis with an overall goal of creating a core set of outcome measures for vasculitis, each of which fulfills the ... process has been informed by several ongoing projects providing data on outcomes of disease activity, disease–related damage, multidimensional health–related quality of life, and patient–reported ratings of the burden of vasculitis. [more...]

Cutaneous vasculitis induced by TNF inhibitors: a report of three cases
Modern Rheumatology, 10/16/2009

Fujikawa K et al. – We describe 3 rheumatoid arthritis (RA) patients with anti-tumor necrosis factor (TNF) therapy-induced cutaneous vasculitis. Two patients required oral corticosteroid, the efficacy of which was observed to ... cutaneous vasculitis 2 cases induced by infliximab 3rd case (cutaneous vasculitis found early at start of therapy) induced by etanercept Skin biopsy obtained in 2 patients Results Histology-proven leukocytoclastic vasculitis in 2 patients 1 [more...]

Analysis of T-cell receptor usage in myeloperoxidase-antineutrophil cytoplasmic antibody-associated renal vasculitis
Clinical and Experimental Nephrology, 10/09/2009

Hirayama K et al. – There was no difference in bacterial superantigens between controls and MPO–ANCA–associated vasculitis patients because of the absence of specific usage of TCR–V[beta ... rather than superantigens may be associated with the pathogenesis of MPO–ANCA–associated vasculitis. [more...]

Mechanisms and markers of vascular damage in ANCA-associated vasculitis
Autoimmunity, 10/05/2009

Haubitz M et al. – Such effects may well contribute to a pro–inflammatory environment in ANCA–associated small–vessel vasculitis and in vascular disease in general. Here, the authors review mechanisms ... associated vasculitis and put these findings into perspective. [more...]

Antineutrophil Cytoplasmic Antibody-Associated Vasculitis Complicated With Diffuse Alveolar Hemorrhage: A Study of 12 Cases
Journal of Clinical Rheumatology (JCR), 10/12/2009

Lin Y et al. – DAH is the most serious complication of ANCA–associated vasculitis. The episode of DAH always occurs simultaneously with multiple system ... dyspnea and new infiltration of bilateral lungs. Prompt bronchoalveolar lavage can be helpful for timely diagnosis of the patients without overt hemoptysis and a useful tool to exclude pulmonary infection. [more...]

Update in paediatric vasculitis
Best Practice & Research: Clinical Rheumatology, 10/27/2009

Ozen S et al. – This review concentrates on recent changes proposed for the classification of paediatric vasculitis and advances in the concepts of aetiopathogenesis. Availability of improved classification criteria for children should prompt planning for ... controlled studies for the treatment of these rare but important diseases. [more...]

Clinicoepidemiological manifestations of RPGN and ANCA-associated vasculitides: an 11-year retrospective hospital-based study in Japan
Modern Rheumatology, 10/14/2009

of vasculitis and infectious episodes after repeated and prolonged treatments with immunosuppressants. Present analysis further confirms the epidemiological and serological differences in ANCA-related RPGN between Japan and Europe, and reinforced the fact that ANCA-associated vasculitis is the most ... who were admitted in hospital over past 11 years and who could be basically followed for more than 1 year Incidence of ANCA-related vasculitis, the presence of (MPO)/proteinase 3 (PR3)-ANCA and clinical outcomes followed As there were no PR3-ANCA single positive and/or WG patients [more...]

Novel expression signatures identified by transcriptional analysis of separated leukocyte subsets in SLE and vasculitis
Annals of Rheumatic Diseases, 10/22/2009

Lyons PA et al. – The analysis of leucocyte subsets enabled the identification of gene signatures of both pathogenic relevance and with better disease discrimination than those ... prognostic biomarkers in autoimmune disease Methods 44 vasculitis patients, 13 SLE patients and 25 age and sex-matched controls enrolled CD4 and CD8 T cells, B cells, monocytes and neutrophils isolated from each patient and, together with unseparated peripheral blood [more...]