All-Trans Retinoic Acid-Induced Focal Myositis, Synovitis, and Mononeuritis
Journal of Clinical Rheumatology (JCR), 10/14/2009
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Yu W et al. – Here the authors report a patient with newly diagnosed acute promyelocytic leukemia who developed acute focal myositis, synovitis, and possible vasculitis, after receiving all–trans retinoic acid ... literature on this rare clinical entity, all–trans retinoic acid–induced myositis. This condition can manifest as fever, myalgia, arthralgia, and Sweet syndrome, accompanied by distinct magnetic resonance findings involving the lower extremity musculature. Treatment consists of ... pharmacology,pharmacology/therapy,side effects
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Voriconazole-Associated Myositis
Journal of Clinical Rheumatology (JCR), 10/22/2009
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Shanmugam VK et al. – The authors present a 34–year–old female African American renal transplant recipient, with a prior history of probable statin–induced myopathy, who developed severe generalized weakness with marked elevation of muscle ... increased use of triazoles in immunosuppressed and transplant recipients, it is important for rheumatology consultants to include this entity in their differential diagnosis of weakness in such patients.
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Melting Muscles: Novel H1N1 Influenza A Associated Rhabdomyolysis
The Pediatric Infectious Disease Journal, 10/27/2009
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D'Silva D et al. – The case demonstrates the novel virus' capacity for causing significant disease. Myositis and the possibility of rhabdomyolysis should be considered in any individual presenting with influenza–like symptoms in which severe
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Treatment of adult inflammatory myositis with rituximab: An emerging therapy for refractory patients
Journal of Clinical Rheumatology (JCR), 10/08/2009
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Shefali M et al. – Early uncontrolled clinical experience indicates that rituximab may be a valuable therapeutic agent for treatment of refractory IIM. Further investigation regarding the optimal
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Inflammatory myopathies
Zeitschrift für Rheumatologie, 10/07/2009
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myopathies. This review focuses on the clinical features, diagnostic techniques, pathogenesis and therapy of immunogenic myopathies. Besides myositis associated with other autoimmune disorders, dermatomyositis is the most common immunogenic myopathy.
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A case of relapsing flitting bilateral idiopathic orbital inflammation
Pediatric Radiology, 10/12/2009
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Browne MA et al. – This can be called orbital myositis if the inflammation is predominantly in the orbital muscles. It is a diagnosis of exclusion based on clinical, radiological, and if necessary, histological findings
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Favorable Outcome of Juvenile Dermatomyositis Treated without Systemic Corticosteroids
The Journal of Pediatrics, 10/27/2009
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all. No serious treatment complications were observed; headaches were reported by 3 patients receiving IVIG. Two patients had a myositis flare after discontinuing all medications for more than 1 year; complete resolution of symptoms was observed after either 1 or 2 further doses of
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Factors Associated With Nontraumatic Rhabdomyolysis and Acute Renal Failure of Children in Taiwan Population
Pediatric Emergency Care, 10/22/2009
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Wu CT et al. – The series confirmed the clinical expectation and showed that viral myositis accounted for more than half of the cases. Physical exertion was the second. Seizure disorder and sepsis were the third most frequent causes. These
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Serum cardiac Troponin T, but not Troponin I, is elevated in idiopathic inflammatory myopathies
Journal of Rheumatology, 10/20/2009
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IIM (69 observations) who satisfied our inclusion criteria identifiedPrimary diagnosis polymyositis in 23, dermatomyositis in 16, and myositis associated with connective tissue disease in 10 patients 33/49 women with average age 45.8 y28 patients with IIM had simultaneous
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Vascular involvement in the pathogenesis of idiopathic inflammatory myopathies
Autoimmunity, 10/05/2009
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associated molecular alterations in muscle in patients with IIMs. This review will highlight some of the most important findings that elucidate the role of vascular endothelial cell dysfunction and hypoxia in the pathogenesis of IIMs.
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