Psychiatry Medical News about Antidepressive Agents

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Trends in prescribing and self-poisoning in relation to UK regulatory authority warnings against use of SSRI antidepressants in under-18-year-olds
British Journal of Clinical Pharmacology, 11/02/09

Bergen H et al. – The reduction in both prescribing and self–poisoning with SSRI antidepressants (except fluoxetine) following the MHRA warning is in keeping with reduced availability of these drugs. There was some evidence of substitution from other SSRIs to fluoxetine for use in self–poisoning. Importantly, overall rates of nonfatal self–harm and self–poisoning did not change, indicating no substitution of method or increases in self–injury.

Glutamate-based antidepressants: 20 years on
Trends in Pharmacological Sciences, 10/29/09 Relevance Score: 66%

The Role of Sodium Channels in the Mechanism of Action of Antidepressants and Mood Stabilizers
Current Drug Targets, 10/30/09 Relevance Score: 64%

Direct agonist activity of tricyclic antidepressants at distinct opioid receptor subtypes
Journal of Pharmacology and Experimental Therapeutics, 10/26/09 Relevance Score: 64%

Early induction of CREB activation and CREB-regulating signalling by antidepressants
International Journal of Neuropsychopharmacology, 10/21/09 Relevance Score: 64%

Vilazodone, a novel dual-acting serotonergic antidepressant for managing major depression
Expert Opinion on Investigational Drugs, 10/02/09 Relevance Score: 64%