Aspergers syndrome and high-functioning autism: language, motor and cognitive profiles
European Child and Adolescent Psychiatry, 10/12/2009
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motor impairment and level of psychosocial adaptation question the validity of the distinction between AS and HFA within the category of pervasive developmental disorders.
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Medication and Parent Training in Children With Pervasive Developmental Disorders and Serious Behavior Problems: Results From a Randomized Clinical Trial
Journal of the American Academy of Child and Adolescent Psychiatry, 11/09/2009
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Aman MG et al. – Medication plus PT resulted in greater reduction of serious maladaptive behavior than MED in children with PDDs, with a
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Sugar-coaters and Straight Talkers: Communicating About Developmental Delays in Primary Care
Pediatrics, 10/01/2009
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Sices L et al. – Most mothers reported a preference for a nonalarmist style of communication when developmental delays are suspected. In contrast, some mothers preferred a more direct style ... s development. The importance of preparation to accept information about developmental delays emerged as a theme in all groups. Elements contributing to preparedness included information about expected developmental skills, suggestions for promoting skills, and a specific time frame for follow&ndash ... This information can inform primary care providers' approaches to monitoring and screening the development of young children and to communicating with parents regarding suspected developmental delays.
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Effects of Individualized Developmental Care in a Randomized Trial of Preterm Infants <32 Weeks
Pediatrics, 10/13/2009
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Maguire CM et al. – NIDCAP developmental care had no effect on respiratory support, days of intensive care, growth, or neuromotor development at term age.
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Helping Young Men Thrive: Positive Youth Development and Men's Health
American Journal of Men's Health, 11/18/2009
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Vo DX et al. – Positive youth development (PYD) is a strong and growing field that complements the traditional problem–focused view of youth, and describes and promotes the healthy development and positive outcomes of young people ... s developmental assets model have guided researchers and practitioners in better understanding the process of PYD and the effectiveness of community interventions to promote PYD. The PYD literature lacks a coherent guiding framework to describe gender differences in positive development, which in
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Global drug development in cancer: a cross-sectional study of clinical trial registries
Annals of Oncology, 10/20/2009
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Seruga B et al. – Drug development in cancer is costly and may be directed toward ‘profitable’ cancers of the more developed regions (MDR) as compared with those of the less developed regions (LDR) of the ... the authors describe drug development in relation to cancer type and geographic location. Lethal cancers that are common in the LDR (e.g. stomach, liver and esophageal cancers) deserve greater emphasis for drug development.
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Drug development for orphan diseases in the context of personalized medicine
Translational Research, The Journal of Laboratory and Clinical Medicine, 11/20/2009
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Brewer GJ – The authors present his own 2 examples of the positive and the negative aspects of orphan drug development, and he end this article by giving recommendations on how we might succeed both in developing ... orphan drugs and in rescuing the pharmaceutical industry from its impending economic collapse.
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Bayer CropScience Opens State of the Art Cotton Research and Development Center in Lubbock
BayNews International, 11/06/2009
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Bayer CropScience officially opened its new Cotton Research and Development Laboratory in Lubbock, Texas. The new 12,000 square–foot laboratory is the latest in a series of new research and development facilities being opened by Bayer ... America and the only one focused solely on delivering innovations in the world’s most important fiber crop: cotton.
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ALX4 dysfunction disrupts craniofacial and epidermal development
Human Molecular Genetics, 11/05/2009
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Kayserili H et al. – The data indicate that ALX4 plays a critical role both in craniofacial development as in skin and hair follicle development in human.
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Proposals for model-based c medicinal development within the current European Union regulatory framework
British Journal of Clinical Pharmacology, 11/02/2009
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Manolis E et al. – The authors attempt to identify the regulatory framework for the use of M&S in paediatric medicinal development and to make proposals for model–based paediatric medicinal development. The objective is ... to open the discussion between industry, academia, paediatricians and regulators on the optimal use of M&S in paediatric medicinal development.
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