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Role of aggrecanase 1 in Lyme arthritis
Arthritis & Rheumatism, 11/01/06
Aruna K. Behera, et al. - Arthritis is one of the hallmarks of late-stage Lyme disease...Conclusion: The induction of ADAMTS-4 by B burgdorferi results in the cleavage of aggrecan, which may be an important first step that leads to permanent degradation of cartilage
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