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Patient-reported-outcomes in subjects with painful lumbar or cervical radiculopathy treated with pregabalin: evidence from medical practice in primary care settings
Rheumatology International, 10/08/09
Saldana MT et al. – The objective of this study was to evaluate the effect of pregabalin in painful cervical or lumbosacral radiculopathy treated in Primary Care settings under routine clinical practice.In routine medical practice, monotherapy or add–on pregabalin is associated with substantial pain alleviation and associated symptoms improvements in painful cervical or lumbosacral radiculopathy.
Methods- Observational, prospective 12–week secondary analysis
- Male and female above 18 years, naïve to PGB, with refractory chronic pain secondary to cervical/lumbosacral radiculopathy were enrolled
- SF–MPQ, Sheehan Disability Inventory, MOS Sleep Scale, Hospital Anxiety and Depression Scale and EQ–5D administered
- After 12 weeks, significant improvements in pain, associated symptoms of anxiety, depression and sleep disturbances, general health; level of disability observed in 3 groups, being significantly greater in PGB groups
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