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Interleukin-12 gene polymorphism and cervical cancer risk
American Journal of Clinical Oncology, 10/06/09

Tamandani K et al. – This is the first study to provide an evidence for the association of IL-12&beta (1188A/C) gene polymorphism with the risk of cervical cancer.

• DNA isolated from peripheral blood of 200 patients with cervical cancer and 200 healthy controls
• Polymerase chain reaction restriction fragment length polymorphism used for detection of IL-12 &beta (1188A/C) gene polymorphism

• Was observed that genotypes AC increase the risk of cervical cancer
• Strength of risk in passive smokers with AC and AC + CC genotypes increased to more than 2.8 times in comparison with nonsmoker with AA genotype

Today in Basic Science/Genetics...keeping you current

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Expression of Hiwi in human esophageal squamous cell carcinoma is significantly associated with poorer prognosis
BMC Cancer, 12/09/09

Tumour markers predictive of successful treatment of breast cancer with primary endocrine therapy in patients over 70 years old: A prospective study
Critical Reviews in Oncology/Hematology, 12/09/09

Gene expression profiling identifies emerging oncogenic pathways operating in extranodal NK/T-cell lymphoma, nasal-type
Blood, 12/09/09

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Today in Gynecologic Oncology...keeping you current

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Prognostic significance of Dicer expression in ovarian cancer - link to global microRNA changes and oestrogen receptor expression
The Journal of Pathology, 12/09/09

Diet and predictors of dietary intakes in women with family history of breast and/or ovarian cancer
Cancer Epidemiology, 12/09/09

Activation of hedgehog signaling is not a frequent event in ovarian cancers
Molecular Cancer, 12/09/09

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