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Glucocorticoids inhibit the innate immune system of human corneal fibroblast through their suppression of toll-like receptors
Molecular Vision, 11/25/09
Jin X et al. – Glucocorticoids, such as hydrocortisone, can inhibit the expression of TLR2 and TLR4 on HCFs, and thus may increase susceptibility to cornea infections. This results suggest that topical glucocorticoids may affect the cornea's innate immunity through TLRs.
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