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Impact on the Corneal Endothelium of Mitomycin C During Photorefractive Keratectomy
Journal of Refractive Surgery, 10/16/09
Roh DS et al. – Although all of the basic science studies reviewed highlight the toxicity of MMC on the corneal endothelium, current clinical studies are less conclusive. Given the corneal penetration of MMC and the fragile nature of the corneal endothelium, additional follow–up studies are needed to determine the long–term impact of MMC usage during PRK on the corneal endothelium.
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