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Nicotinamide inhibits Propionibacterium acnes-induced IL-8 production in keratinocytes through the NF-kB and MAPK pathways
Journal of Dermatological Science, 10/06/09
Grange PA et al. – The authors' results indicate that nicotinamide inhibits IL–8 production through the NF–kB and MAPK pathways in an in vitro keratinocytes/P. acnes model of inflammation. Keratinocytes involved in the innate immune response may be a suitable target for treatment during the early phase of inflammation.
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