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Top kaposi Articles in Ophthalmology

Regulation of angiogenesis in malignancies associated with Epstein–Barr virus and Kaposi's sarcoma-associated herpes virus
Future Microbiology, 09/18/2009
Sakakibara S et al. – The human Epstein–Barr virus and Kaposi’s sarcoma–associated herpesvirus critically contribute to the pathogenesis of selected tumor types, including nasopharyngeal carcinoma and Kaposi's sarcoma ... is robust and often disrupted. Lymphangiogenesis, the process by which new lymphatic vessels are formed, is also induced in Epstein–Barr virus and Kaposi’s sarcoma–associated herpesvirus–associated malignancies and in some cases may contribute to metastasis. [more...]

Dermoscopy of Kaposis sarcoma: Areas exhibiting the multicoloured rainbow pattern
Journal of the European Academy of Dermatology and Venereology, 09/17/2009
Hu SCS et al. – The most frequent dermoscopic patterns in Kaposi's sarcoma were found to be bluish–reddish coloration, the 'rainbow pattern', and scaly surface. The rainbow pattern is a dermoscopic ... not been previously described. The authors propose that dermoscopy, as an adjunct to clinical examination, may enhance accuracy in the preoperative diagnosis of Kaposi's sarcoma. [more...]

Leprosy and Kaposi sarcoma presenting as an immune reconstitution inflammatory syndrome in a patient with AIDS
Journal of the American Academy of Dermatology, 08/26/2009
Medeiros S et al. – The simultaneous presence of infectious organisms within cutaneous lesions of Kaposi sarcoma in persons with AIDS has been demonstrated. The authors describe a ... concurrent leprosy and Kaposi sarcoma presenting as an immune reconstitution inflammatory syndrome in the setting of AIDS. [more...]

Human herpesvirus-8 and kaposi sarcoma after kidney transplantation: Mechanisms of tumor genesis
Iranian Journal of Kidney Diseases, 08/03/2009
Ahmadpoor P – Article reviews the tumor genesis mechanism of human herpesviruses (HHV)-8 in kidney transplant recipients.

  • The incidence of iatrogenic Kaposi sarcoma (KS), which develops ... IL-6 or viral macrophage inflammatory ptoyeins
  • By this capability, HHV-8 is able to control key aspects of cell regulation, allowing the cell to replicate, to prevent cell death, and to shut off immune responses in infected cells
[more...]

Positive staining of tumor-stage Kaposi sarcoma with lymphatic marker D2-40
Journal of the American Academy of Dermatology, 08/04/2009
Dubina M et al. – In a study to investigate the origin of neoplastic cells in Kaposi sarcoma (KS), it was reprted that the origin of neoplastic cells in KS may be lymphatic or mixed lymphatic and vascular.

Results
  • 5 cases were reported of tumor-stage KS that showed positive staining with lymphatic marker D2-40.
[more...]

Immunohistochemistry in Kaposis sarcoma
Clinical and Experimental Dermatology, 10/28/2009
Pantanowitz L et al. – The importance of immunohistochemistry (IHC) to understanding, ability to confidently diagnose and treat Kaposi's sarcoma (KS) has grown steadily in the past few decades. IHC has been performed on many KS specimen types, with ... antibodies. Therefore, it is not surprising that IHC has helped unravel the histogenesis, understand the pathogenesis and facilitate the diagnosis of KS and identify novel therapeutic targets in the disease. [more...]

HHV8-positive, HIV-negative multicentric Castlemans disease: early and sustained complete remission with rituximab therapy without reactivation of Kaposi sarcoma
International Journal of Hematology, 09/24/2009
Nicoli P et al. – No reactivation of the Kaposi sarcoma found in a lymph node of one of the patients was observed. The report, along with additional data present in the [more...]

Effect of immunodeficiency, HIV viral load, and antiretroviral therapy on the risk of individual malignancies (FHDH-ANRS CO4): a prospective cohort study : The Lancet Oncology
The Lancet Oncology - Online First, 10/12/2009
specific screening programmes need to be assessed in patients with HIV.

Methods

  • Incidence of both AIDS-defining cancers (Kaposi's sarcoma, non-Hodgkin lymphoma, and cervical cancer) and non-AIDS-defining cancers (Hodgkin's lymphoma, lung cancer, liver cancer, and anal cancer ... rate ratios (RR) ranged from 1·9 (95% CI 1·3—2·7) for CD4 counts 350—499 cells per ?L to 25·2 (17·1—37·0) for counts less than 50 cells per ?L for Kaposi's sarcoma , from 1·3 (0·9—2·0) to 14·8 (9·7—22·6) for non-Hodgkin lymphoma , from 1·2 (0·7—2·2) to 5·4 (2·4—12·1) for Hodgkin's lymphoma , from 2 ... strong effect of current CD4 (RR 0·7 per log2, 95% CI 0·6—0·8)
  • Risk of Kaposi's sarcoma and non-Hodgkin lymphoma increased for current plasma HIV RNA greater than 100 000 copies per mL compared with patients with controlled viral load (RR 3·1, 95% CI 2·3—4·2; and 2·9, 2·1—3·9), whereas cART [more...]

Cause-specific mortality in classic Kaposi's sarcoma: a population-based study in Italy
British Journal of Cancer, 08/27/2009
Ascoli V et al. – Though referring specifically to Italy, the results are informative for other countries and populations and all cases of CKS in general. [more...]

Kaposi sarcoma-associated herpesvirus (KSHV): Molecular biology and oncogenesis
Cancer Letters, 08/17/2009
Wen KW et al. – The authors discuss the three KSHV–associated malignancies, KSHV genome, latent and lytic aspects of the viral lifecycle, putative viral oncogenes, as well as therapeutic regimens used for ... the treatment of KS, PEL, and MCD. [more...]

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