Toxic corneal ulcer: a frequent and sight-threatening disease
European Journal of Ophthalmology, 11/11/2009
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Sacchetti M et al. – Toxic corneal ulcer is a frequent disease that can potentially lead to permanent visual impairment. A high–dose regimen is the major risk factor for corneal toxic ulcer development and poor visual
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Practice Patterns in the Management of Fungal Corneal Ulcers
Cornea, 10/09/2009
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Loh AR et al. – There appears to be significant variation in the management of fungal corneal ulcers. Although natamycin was the most commonly used treatment for ulcers caused by filamentous fungi, voriconazole was the most
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Solve the Mystery of Corneal Thinning Disorders
Review of Ophthalmology, 10/02/2009
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Bethke W – Everyone likes a good mystery, except when it involves finding the cause of peripheral corneal thinning. Possible causes abound, from autoimmune disease to staph hypersensitivity ulcers, and it’s up to the ophthalmologist to sort ... with the right one. In this article, corneal specialists explain how you can determine the cause of a patient’s thinning peripheral cornea and start the proper treatment as quickly as possible.
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Detection of virulence factors in Serratia strains isolated from contact lens-associated corneal ulcers
Acta Ophthalmologica, 10/23/2009
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Pinna A et al. – The ability to produce alkaline protease and gelatinase may play a major role in the pathogenesis of contact lens–related Serratia keratitis. Several types of
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Determination of corneal volume from anterior topography and topographic pachymetry: application to healthy and keratoconic eyes
Ophthalmic and Physiological Optics, 10/29/2009
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Cervino A et al. – Corneal volume is a useful parameter for characterising dystrophic corneas and can aid in the detection of rare anomalies which are hardly detected with corneal ... topography and/or central corneal thickness evaluation. A potentially useful measure of corneal volume can be calculated from anterior corneal topography and topographic pachymetry data. Values obtained are in good agreement with previous studies using corneal tomography techniques. The methodology
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Exploring the complex care of the diabetic foot ulcer
JAAPA, 10/30/2009
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Jones R – Many amputations resulting from diabetic foot ulcers are preventable with a thorough evaluation and aggressive treatment. The most important primary preventive measures are properly fitting socks and shoes and good control of ... the diabetic foot ulcer. The primary objective is to heal the ulcer and prevent amputation. Patients with an infected foot ulcer benefit from early, aggressive treatment that encompasses debridement, good wound care, and pressure relief. An infected diabetic foot ulcer requires close supervision ... the foot is acceptable initially, but a technetium scan or MRI may be warranted to confirm the clinical assessment. Antibiotic coverage should be broad spectrum and tailored to the patient.
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Impact on the Corneal Endothelium of Mitomycin C During Photorefractive Keratectomy
Journal of Refractive Surgery, 10/16/2009
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Roh DS et al. – Although all of the basic science studies reviewed highlight the toxicity of MMC on the corneal endothelium, current clinical studies are less conclusive. Given the corneal penetration of MMC ... fragile nature of the corneal endothelium, additional follow–up studies are needed to determine the long–term impact of MMC usage during PRK on the corneal endothelium.
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Effect of Aging on Corneal Biomechanical Parameters Using the Ocular Response Analyzer
Journal of Refractive Surgery, 10/16/2009
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Corneal biomechanical parameters are significantly decreased by aging without significant changes in central corneal thickness or IOP, suggesting that age–related structural changes resulting from collagen ... linking may lead to a reduction of corneal biomechanical variables independent of central corneal thickness or IOP.
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Effects of Altered Corneal Stiffness on Native and Postoperative LASIK Corneal Biomechanical Behavior: A Whole-eye Finite Element Analysis
Journal of Refractive Surgery, 10/19/2009
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Roy AS et al. – Differences in the corneoscleral stiffness relationship affect simulated refractive outcomes after LASIK and may be a source of ... balance between central corneal flattening and pre–ectatic weakening of the corneal apex not demonstrated in previous computational models and provides insight into under– and overcorrection in myopic LASIK and the previously unexplained phenomenon of corneal flattening after therapeutic
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Factors of importance to the development of pressure ulcers in the care trajectory: perceptions of hospital and community care nurses
Journal of Clinical Nursing, 11/12/2009
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Athlin E et al. – The study both confirmed previous findings and added new knowledge about factors that may affect pressure ulcer in the trajectory of care. The informants' views ... towards the care of pressure ulcers could, along with their views on the organisation of care, increase the understanding of the occurrence of pressure ulcers. The need for development and clarification of the organisation and responsibility of pressure ulcer care in the care trajectory was stressed ... dermatology
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