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See Latest ArticlesCurrent therapies to shorten postoperative ileus
Cleveland Clinic Journal of Medicine, 11/04/09
Johnson MD et al. – Postoperative ileus delays hospital discharge, increases costs, and contributes to adverse outcomes. A variety of neural and chemical factors are involved. To shorten the duration of postoperative ileus, we may need to establish standard plans of care that favor earlier feeding, use of nasogastric tubes only on a selective basis, and prokinetic drugs as needed.
- Postoperative ileus can selectively affect the stomach, small intestine, or large intestine, each with different causes and clinical presentation and each managed differently.
- Laparoscopic surgery is associated with a shorter duration of postoperative ileus compared with open surgery.
- Epidural anesthesia reduces the need for opiate analgesia after surgery and thus shortens the duration of postoperative ileus.
- Drugs are being developed that block the effects of opiates on the gut while preserving their pain–relieving properties.
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