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Ruddell, M., et al. - Growth in antidepressant prescribing is a well-recognised phenomenon in developed countries. In stroke care, the evidence of effectiveness from systematic reviews is surprisingly weak. We therefore decided to undertake a randomised controlled trial comparing fluoxetine to placebo...Conclusions: In addition to the predicted practical problems of conducting an RCT in an elderly frail population, it became clear that most clinicians are not in equipoise about the value of antidepressant medication despite the lack of strong evidence for its effectiveness

Today in Neuro/Psych pharmacology...keeping you current

Probable levetiracetam-associated depression in the elderly: Two case reports
The American Journal of Geriatric Pharmacotherapy, 12/18/09

Treatment retention with risperidone long-acting injection: 24-month results from the Electronic Schizophrenia Treatment Adherence Registry in six countries
Current Medical Research and Opinion, 12/18/09

Berberine: a plant alkaloid with therapeutic potential for central nervous system disorders
Phytotherapy Research, 12/18/09

Today in Stroke/Vascular...keeping you current

The decrease in procarboxypeptidase U (TAFI) concentration in acute ischemic stroke correlates with stroke severity, evolution and outcome
Journal of Thrombosis and Haemostasis, 12/18/09

Gender differences in patients with acute ischemic stroke
Women's Health, 12/18/09

Observation of the embolus protection filter for carotid artery stenting
Surgical Neurology, 12/18/09


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