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Fluoxetine vs placebo for depressive symptoms after stroke: failed randomised controlled trial
International Journal of Geriatric Psychiatry, 08/30/07
Ruddell, M., et al. - Growth in antidepressant prescribing is a well-recognised phenomenon in developed countries. In stroke care, the evidence of effectiveness from systematic reviews is surprisingly weak. We therefore decided to undertake a randomised controlled trial comparing fluoxetine to placebo...Conclusions: In addition to the predicted practical problems of conducting an RCT in an elderly frail population, it became clear that most clinicians are not in equipoise about the value of antidepressant medication despite the lack of strong evidence for its effectiveness
Today in Neuro/Psych pharmacology...keeping you current
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Escitalopram and Venlafaxine for the Prophylaxis of Migraine Headache Without Mood Disorders
Clinical Neuropharmacology, 10/02/09
Nortriptyline and gabapentin, alone and in combination for neuropathic pain: a double-blind, randomised controlled crossover trial
The Lancet, 10/13/09
Cardiometabolic Risk of Second-Generation Antipsychotic Medications During First-Time Use in Children and Adolescents
JAMA, 10/29/09
Today in Stroke/Vascular...keeping you current
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Antithrombotic medication for stroke prevention
Expert Review of Cardiovascular Therapy , 10/20/09
New Anticoagulants for Atrial Fibrillation
Seminars in Thrombosis and Hemostasis, 09/15/09
Prevention and management of stroke in very elderly patients
The Lancet Neurology, 10/15/09
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