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Cerebrospinal hypocretin, daytime sleepiness and sleep architecture in Parkinson's disease dementia
Brain, 10/28/09

Compta Y et al. – Excessive daytime sleepiness is more frequent in Parkinson's disease patients with dementia than Parkinson's disease patients without dementia, but lumbar cerebrospinal fluid hypocretin–1 levels are normal and unrelated to severity of sleepiness or the cognitive status. Lumbar cerebrospinal fluid does not accurately reflect the hypocretin cell loss known to occur in the hypothalamus of advanced Parkinson's disease. Alternatively, mechanisms other than hypocretin cells dysfunction may be responsible for excessive daytime sleepiness and the sleep architecture alterations seen in these patients.

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Widely Used Cholesterol-lowering Drug May Prevent Progression Of Parkinsons Disease
ScienceDaily, 11/10/09 Relevance Score: 70%

GIGYF2 mutations are not a frequent cause of familial Parkinson's disease
Parkinsonism & Related Disorders, 11/09/09 Relevance Score: 69%

Effects of optimism/pessimism and locus of control on disability and quality of life in Parkinson's disease
Parkinsonism & Related Disorders, 10/29/09 Relevance Score: 69%

Sleep disturbances in Malaysian patients with Parkinson's disease using polysomnography and PDSS
Parkinsonism & Related Disorders, 10/29/09 Relevance Score: 69%

Condition Raises Parkinsons Risk 5-Fold
Ivanhoe, 10/27/09 Relevance Score: 69%