Evidence of descending inhibition deficits in atypical but not classical trigeminal neuralgia
Pain, 10/20/2009
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Leonard G et al. – The aim of the present study was to evaluate the functional integrity of the diffuse noxious inhibitory controls (DNIC) in (1) a group of patients with classical trigeminal neuralgia (CTN), (2) a group of patients with atypical trigeminal neuralgia (ATN), and (3 ... differs between classical TN (CTN) and atypical TN (ATN) and that a deficit in descending inhibition may further contribute to the pain experienced by patients with ATN.
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Hypothalamic stimulation for trigeminal neuralgia in multiple sclerosis patients: efficacy on the paroxysmal ophthalmic pain
Multiple Sclerosis, 10/09/2009
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Cordella R et al. – Deep brain stimulation may be considered as an adjunctive procedure for treating refractory paroxysmal pain within the first trigeminal division so ... reflex impairment that is known to follow ablative procedures.
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Microvascular decompression in patients with isolated maxillary division trigeminal neuralgia, with particular attention to venous pathology
Neurosurgical Focus, 11/03/2009
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Sekula Jr. RF et al. – The authors confirmed that patients with isolated V2, or maxillary division, trigeminal neuralgia (TN) were more likely to be female, tended toward an ... and fared just as well as those presenting with typical pain.
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Postherpetic Neuralgia: From Preclinical Models to the Clinic
Neurotherapeutics, 10/05/2009
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Delaney A et al. – Postherpetic neuralgia (PHN), a common complication of herpes zoster, which results from reactivation of varicella zoster virus, is a challenging neuropathic pain syndrome. The incidence and severity of herpes ... of preclinical outcomes to the clinic may lead to more efficacious treatment options. Here the authors give an overview of recent findings from preclinical models and clinical research on PHN.
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C1 lateral mass screw-induced occipital neuralgia: a report of two cases
European Spine Journal, 10/28/2009
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Conroy E et al. – It has been reported that the absence of threads on the upper portion of the long shank screw may protect against neural irritation. However, insertion of the C1 lateral mass screw necessitates careful ... mass. Two patients in these series suffered occipital neuralgia post–insertion of C1 lateral mass screws. This highlights the potential for damage to the C2 nerve root during C1 lateral mass screw placement.
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Tinnitus in postherpetic neuralgia
The Journal of Headache and Pain, 10/26/2009
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De Marinis M et al. – The authors describe a woman who developed postherpetic neuralgia (PHN) located on the skin areas of the left ophthalmic division of the fifth cranial nerve without ocular involvement. PHN was associated with tinnitus, which was ... of pain. Tinnitus was responsive to treatment with duloxetine, 60 mg daily, and subsided when the PHN resolved. This is the first description of tinnitus in PHN.
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The treatment of first division idiopathic trigeminal neuralgia with radiofrequency thermocoagulation of the peripheral branches compared to conventional radiofrequency
Journal of Clinical Neuroscience, 10/15/2009
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Huibin Q et al. – The immediate efficacy rates were 95% and 93% in groups 1 and 2, respectively. The recurrence rates of idiopathic trigeminal neuralgia (ITN) at the ... significant differences between groups 1 and 2 at any time. This study demonstrates that trigeminal peripheral division radiofrequency thermocoagulation (PRT) is an effective way to treat first division ITN.
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Tailored neurectomy for treatment of postherniorrhaphy inguinal neuralgia
Surgery, 10/19/2009
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Loos MJ et al. – Groin hernia repair occasionally leads to severe chronic pain associated with entrapped or damaged nerves...A selective operative neurectomy for postherniorrhaphy groin neuralgia provides good long–term pain relief in ... feel responsible for this iatrogenic complication and should consider incorporating selective neurectomy in their surgical armamentarium.
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Advanced age as a contraindication to microvascular decompression for drug-resistant trigeminal neuralgia: evidence of prejudice?
Neurological Sciences, 10/09/2009
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Ferroli P et al. – A retrospective analysis of clinical outcome and complications was performed in 476 patients affected by drug–resistant trigeminal neuralgia who underwent microvascular decompression. As ... significant differences were observed between Groups 1 and 2. These findings seem to support the idea that microvascular decompression is not a dangerous surgical procedure in patients over the age of 65 years.
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Ultrastructure and immunohistochemistry of the trigeminal peripheral myelinated axons in patients with neuralgia
Clinical Neurology and Neurosurgery, 11/05/2009
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Marinkovic S et al. – The pathological changes affect not only the central nerve fibers of the trigeminal nerve roots (TNRs), but also some of the peripheral axons, their myelin ... which could participate in the pathophysiological mechanism underlying the trigeminal neuralgia.
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