Lactic Acidosis Associated With Metformin in a Patient With Type 2 Diabetes With No Contraindication
The Endocrinologist, 11/13/2009
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Dora JM et al. – Metformin is a frequent treatment for overweight type 2 patients with diabetes. Lactic acidosis (LA) is considered to be a rare, but potentially lethal adverse event ... with LA should be kept in mind when dealing with acute situations such as that presented by the patient described.
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Fatal Lactic Acidosis Associated With the Use of Combination Oral Medications to Treat Reactivation of Hepatitis B
Journal of Clinical Gastroenterology, 10/22/2009
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Cohen SM et al. – Oral nucleostide analogs for the treatment of hepatitis B virus (HBV) infection are well tolerated with minimal side effects. These agents do carry a Food and ... Administration black box warning about the development of fatal lactic acidosis on the basis of data from the human immunodeficiency virus literature.
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Cardiac Autonomic Responses to Repeated Shuttle Sprints
International Journal of Sports Medicine, 11/02/2009
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Nakamura FY et al. – The repeated shuttle–sprint ability test was shown to induce comparable levels of lactic acidosis and post–exercise autonomic state as the 30–15IFT. These levels of metabolic and autonomic states are likely to occur during team
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Impact of normal saline infusion on postoperative metabolic acidosis
Paediatric Anaesthesia, 10/08/2009
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Mann C et al. – Implementing serial Cleff assessment could improve postoperative management by disclosing or excluding hyperchloremia as a cause of acidosis undetectable from SBE alone. Calculating the chloride–driven ... the interpretation of SBE values and can optimize fluid management in postoperative metabolic acidosis.
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Arterial [H+] and the ventilatory response to hypoxia in humans: influence of acetazolamide-induced metabolic acidosis
Lung Cellular and Molecular Physiology, 11/05/2009
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Teppema LJ et al. – The metabolic acidosis was accompanied by a rise in ventilation, a substantial fall in PaCO2 and a parallel leftwards shift of the ventilatory CO2 ... between hypoxic sensitivity and arterial [H+] ([H+a]) to higher values of [H+a] without altering its slope indicating that it did not affect the O2–CO2 interaction. So in contrast to earlier belief CO2 and H+ have separate effects on hypoxic sensitivity.
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Management of distal renal tubular acidosis (RTA) or RTA type I in pregnancy. Two case reports
Portuguese Journal of Nephrology and Hypertension, 10/12/2009
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Casanova C et al. – Joint and multidisciplinary management of these patients by the obstetrician and nephrologist is vital to reduce the maternal –foetal risks that can arise from this ... normal foetal development and a minimal risk for the mother, as it can be observed in the cases herein presented as well as in those described in the literature.
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In vitro tests and modelization of bicarbonate kinetics and mass transfers during online hemodiafiltration
The International Journal of Artificial Organs, 10/30/2009
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Morel H et al. – The data confirmed that online HDF automatically corrects acidosis without creating alkalosis when HCO3 – dialysate concentration is around 30 mmol/L.
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Effects of Persistent CO2 Insufflation During Different Laparoscopic Inguinal Hernioplasty: A Prospective, Randomized, Controlled Study
Journal of Laparoendoscopic & Advanced Surgical Techniques, 10/22/2009
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Zhu Q et al. – Both TAPP and TEP procedures can result in CO2 accumulation, acidosis, increased blood pressure, and decreased heart rate. But, these effects were transient and could be well controlled by appropriate treatments during
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Growth-plate cartilage in chronic renal failure
Pediatric Nephrology, 10/12/2009
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CP et al. – Multiple etiologic factors can contribute to impaired bone growth in renal failure, including suboptimal nutrition, metabolic acidosis, and secondary hyperparathyroidism. Recent findings have also shown the tight connection between chondro/osteogenesis, hematopoiesis, and
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Sorafenib induced tumor lysis syndrome in an advanced hepatocellular carcinoma patient
World Journal of Gastroenterology, 10/06/2009
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hemodialysis was performed. Despite intensive hemodialysis and other supportive therapy, he developed multiple organ failure (liver, renal, and respiratory failure) and metabolic acidosis.
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