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Endothelial Progenitor Cells Possess Monocyte-like Antigen-presenting and T-cell-Co-stimulatory Capacity
Transplantation, 11/25/09
Raemer PC et al. – Although EPC exhibit endothelial–like surface markers, functional characteristics place these cells in a monocytic lineage. EPC also display antigen–presenting capacity similar to monocytes and much stronger than human vascular EC. Significant T–cell–activating potential will have to be expected from EPC when potentially used therapeutically, especially in allogenic transplant settings.
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