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Postnatal adrenalectomy impairs urinary concentrating ability by increased COX-2 and leads to renal medullary injury
Renal Physiology, 08/31/07
Stubbe, J., et al. - It is concluded that mineralocorticoid is required for normal postnatal development of the renal medulla. COX-2 contributes to impaired urine-concentrating ability, NaCl loss, and extracellular volume depletion in postnatal mineralocorticoid deficiency
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