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Sodium Bicarbonate for the Prevention of Contrast Induced-Acute Kidney Injury: A Systematic Review and Meta-analysis
Clinical Journal of the American Society of Nephrology, 10/07/09
Brar SS et al. – A significant clinical and statistical heterogeneity was observed that was largely explained by trial size and published status. Among the large randomized trials there was no evidence of benefit for hydration with sodium bicarbonate compared with sodium chloride for the prevention of CI–AKI. The benefit of sodium bicarbonate was limited to small trials of lower methodological quality.
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