What I tell my patients about contrast medium nephrotoxicity
British Journal of Renal Medicine, 10/27/2009
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Contrast media are colourless solutions, which are used to assist in diagnostic and interventional procedures such as X–rays with dye, angiography (which is used to outline blood vessels), computed tomography (CT) scans and ... These contrast media can occasionally cause kidney damage, especially in patients who already have kidney disease. Contrast media are of different types, some of which are more ‘kidney–friendly’ than others.
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Abdominal 64-MDCT for Suspected Appendicitis: The Use of Oral and IV Contrast Material Versus IV Contrast Material Only
American Journal of Roentgenology, 11/04/2009
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Anderson SW et al. – Patients presenting with nontraumatic abdominal pain imaged using 64–MDCT with isotropic reformations had similar characteristics for the diagnosis of appendicitis when IV contrast material alone was ... oral and IV contrast media were used.
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Gadolinium-Associated Nephrogenic Systemic Fibrosis
American Family Physician, 10/01/2009
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ndash;based contrast agents used in magnetic resonance imaging. Because of this relationship between nephrogenic systemic fibrosis and gadolinium–based contrast agents, the U.S. Food and Drug Administration currently warns against using gadolinium–based contrast agents in patients with a ... reports of nephrogenic systemic fibrosis developing in patients not exposed to gadolinium–based contrast agents, but most patients have the triad of gadolinium exposure through contrast–enhanced magnetic resonance imaging, renal failure, and a proinflammatory state, such as recent
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Systematic Review: Sodium Bicarbonate Treatment Regimens for the Prevention of Contrast-Induced Nephropathy
Annals of Internal Medicine, 11/03/2009
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Zoungas S et al. – This review of 9 published and 14 unpublished trials of sodium bicarbonate suggests that the effect of this agent has been overestimated. Unpublished trials found ... bias. Sodium bicarbonate is probably less effective at preventing contrast–induced nephropathy than is currently thought. Routine use of sodium bicarbonate for prevention of contrast–induced nephropathy is therefore premature.
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Effect of Intravascular Iodinated Contrast Media on Natural Course of End-Stage Renal Disease Progression in Hemodialysis Patients
Cardiovascular and Interventional Radiology, 10/20/2009
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Janousek R et al. – The authors can conclude that residual diuresis is not significantly influenced by intravascular administration of iso–osmolal iodinated contrast agent in ... comparison to natural course of urinary output and residual renal function during end–stage renal disease. This result can help the nephrologist to decide which imaging method/contrast medium to use in dialyzed patients in current practice.
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CT-Guided Biopsies of Pancreatic Lesions: Impact of Contrast Application Prior to versus Following Needle Placement
Academic Radiology, 10/16/2009
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Meier–Meitinger M et al. – CT–guided biopsy of pancreatic lesions with i.v.–contrast application following needle placement is a reliable method and provides ... after contrast enhanced planning CT.
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The time has come to limit the placebo period in rheumatoid arthritis trials to 3 months: A systematic comparison of 3- and 6-month response rates in trials of biologic agents.
Annals of Rheumatic Diseases, 10/08/2009
the contrast in ACR response between experimental and control groups at 3 and 6 monthsResults- 20 trials yielded 15 placebo and 18 active control contrasts (>10,000 patients)
- At 3 months active treatment showed highly significant contrast with placebo for ACR20 ... li>
- As all groups improved further the mean contrast at 6 months was unchanged
- For ACR70 contrast was clearly greater at 6 months due to further improvement only in experimental groups
- In active control trials contrasts were smaller, for ACR50 and-70 these decreased somewhat
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A comparison of the palatability of flavored oral contrasts
The American Journal of Emergency Medicine, 10/05/2009
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Arya R et al. – Dilution of oral contrast media with lemonade, fruit punch, or orange juice is tastier than with water. The choice of the specific juice used to dilute the oral contrast should be individualized based on patient
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Acute Left Ventricular Remodeling After Myocardial Infarction on Transthoracic Echocardiography: A Case Series
Journal of The American Society of Echocardiography, 11/06/2009
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infarction. Endocardial separation from the mid myocardium, echocardiographic contrast penetration into the myocardium, and regional contrast swirling were observed. This case series also illustrates how contrast imaging may enhance recognition of early postinfarction remodeling.
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Highly accelerated first-pass contrast-enhanced magnetic resonance angiography of the peripheral vasculature: Comparison of gadofosveset trisodium with gadopentetate dimeglumine contrast agents
Journal of Magnetic Resonance Imaging, 10/29/2009
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Maki JH et al. – First–pass peripheral CE–MRA using gadofosveset trisodium is feasible
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