Standard vs pH-adjusted and lidocaine supplemented radiocolloid for patients undergoing sentinel-lymph-node mapping and biopsy for early breast cancer (PASSION-P trial): a double-blind, randomised controlled trial
The Lancet Oncology - Online First, 08/07/2009
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or to 1 of 3 other study groups: topical placebo cream and injection of Tc-sulfur colloid containing either sodium bicarbonate (n=35), 1% lidocaine (n=35), or sodium bicarbonate and 1% lidocaine (n=35).The randomisation sequence was computer generated, and all pts and investigators were ... radiocolloid plus bicarbonate, 1.6 for those who received radiocolloid plus 1% lidocaine, and 1.6 for those who received radiocolloid plus bicarbonate and 1% lidocaine.Mean pain rating was 17.5 for the standard-of-care group, 15.4 for the sodium bicarbonate group, 4.6 for the 1% lidocaine ... the sodium bicarbonate plus 1% lidocaine group.SLN identification rates for each group were: 96% for the standard of care, 97% for sodium bicarbonate, 90% for 1% lidocaine, and 90% for sodium bicarbonate plus 1% lidocaine group.
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Systematic Review: Sodium Bicarbonate Treatment Regimens for the Prevention of Contrast-Induced Nephropathy
Annals of Internal Medicine, 11/03/2009
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Zoungas S et al. – This review of 9 published and 14 unpublished trials of sodium bicarbonate suggests that the effect of this agent has been overestimated. Unpublished trials found ... published trials, and formal testing confirmed publication bias. Sodium bicarbonate is probably less effective at preventing contrast–induced nephropathy than is currently thought. Routine use of sodium bicarbonate for prevention of contrast–induced nephropathy is therefore premature ... diagnostics,nephropathies,preventive medicine,fluids and electrolytes,internal medicine,nephrology
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Sodium Bicarbonate for the Prevention of Contrast Induced-Acute Kidney Injury: A Systematic Review and Meta-analysis
Clinical Journal of the American Society of Nephrology, 10/07/2009
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Brar SS et al. – A significant clinical and statistical heterogeneity was observed that was largely explained by trial size and published status. Among the large randomized ... there was no evidence of benefit for hydration with sodium bicarbonate compared with sodium chloride for the prevention of CI–AKI. The benefit of sodium bicarbonate was limited to small trials of lower methodological quality.
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Sodium bicarbonate for prevention of contrast-induced acute kidney injury: a systematic review and meta-analysis
Nephrology Dialysis Transplantation, 08/26/2009
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Hoste EAJ et al. – The incidence of CI–AKI was higher than recently reported, and varied among study cohorts. We found a preventive effect of the use of sodium bicarbonate on the ... mortality. The relative low quality of the individual studies, heterogeneity and possible publication bias means that only a limited recommendation can be made in favour of the use of sodium bicarbonate.
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Halomonas, a Newly Recognized Human Pathogen Causing Infections and Contamination in a Dialysis Center: Three New Species
Medicine, 08/26/2009
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that the RCC became contaminated with these halophilic organisms from bicarbonate used to prepare dialysis fluid, and they persist despite cleaning and flushing procedures because of biofilm in machines and bicarbonate fluid inflow sites. Our experience, together with the review of the literature
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Decreasing pulmonary ventilation through bicarbonate ultrafiltration: An experimental study
Critical Care Medicine, 08/21/2009
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Cressoni M et al. – CO2 removal with bicarbonate ultrafiltration may be an effective treatment for patients with respiratory failure.
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Sodium Bicarbonate versus Sodium Chloride and Oral N-Acetylcysteine for the Prevention of Contrast-Induced Nephropathy in Advanced Chronic Kidney Disease
Journal of Interventional Cardiology, 09/10/2009
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Shavit L et al. – Hydration with sodium bicarbonate is not more effective than hydration with sodium chloride and oral NAC for prophylaxis
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Efficacy of Single-Bolus Administration of Sodium Bicarbonate to Prevent Contrast-Induced Nephropathy in Patients With Mild Renal Insufficiency Undergoing an Elective Coronary Procedure
The American Journal of Cardiology, 10/01/2009
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Tamura A et al. – Single–bolus intravenous administration of sodium bicarbonate in addition to standard hydration can
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A comparative study of ceruminolytic agents
Indian Journal of Otolaryngology and Head & Neck Surgery, 10/07/2009
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of ceruminolytic agents, i.e 2% paradichlorobenzene, 10% sodium bicarbonate, 2.5% acetic acid and normal saline. 2% paradichlorobenzene emerged as the most superior ceruminolytic, closely followed by 10% sodium bicarbonate. 2.5% acetic acid fared moderately while normal saline emerged as the least
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Clinical utility of anion gap in deciphering acid–base disorders
International Journal of Clinical Practice, 09/22/2009
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increase the AG and those that leave the AG unchanged. Delta gap is the comparison between change (delta) in the AG and the change (delta) in bicarbonate (HCO3
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