Top bicarbonate Articles in Nephrology

Systematic Review: Sodium Bicarbonate Treatment Regimens for the Prevention of Contrast-Induced Nephropathy
Annals of Internal Medicine, 11/03/2009

Zoungas S et al. – This review of 9 published and 14 unpublished trials of sodium bicarbonate suggests that the effect of this agent has been overestimated. Unpublished trials found ... published trials, and formal testing confirmed publication bias. Sodium bicarbonate is probably less effective at preventing contrast–induced nephropathy than is currently thought. Routine use of sodium bicarbonate for prevention of contrast–induced nephropathy is therefore premature ... diagnostics,nephropathies,preventive medicine,fluids and electrolytes,internal medicine,nephrology [more...]

Sodium Bicarbonate for the Prevention of Contrast Induced-Acute Kidney Injury: A Systematic Review and Meta-analysis
Clinical Journal of the American Society of Nephrology, 10/07/2009

Brar SS et al. – A significant clinical and statistical heterogeneity was observed that was largely explained by trial size and published status. Among the large randomized ... there was no evidence of benefit for hydration with sodium bicarbonate compared with sodium chloride for the prevention of CI–AKI. The benefit of sodium bicarbonate was limited to small trials of lower methodological quality. [more...]

Bicarbonate-based peritoneal dialysis solution has less effect on ingestive behavior than lactate-based peritoneal dialysis solution
Peritoneal Dialysis International, 11/16/2009

Zheng ZH et al. – The bicarbonate/lactate solution inhibited appetite less than the lactate solution; this was due partially to the use of bicarbonate. The [more...]

Biocompatibility and tolerability of a purely bicarbonate-buffered peritoneal dialysis solution
Peritoneal Dialysis International, 11/17/2009

Weiss L et al. – The use of a purely bicarbonate–buffered low–glucose degradation product solution significantly changes most of the peritoneal effluent markers measured, suggesting an [more...]

Efficacy of Single-Bolus Administration of Sodium Bicarbonate to Prevent Contrast-Induced Nephropathy in Patients With Mild Renal Insufficiency Undergoing an Elective Coronary Procedure
The American Journal of Cardiology, 10/01/2009

Tamura A et al. – Single–bolus intravenous administration of sodium bicarbonate in addition to standard hydration can [more...]

A comparative study of ceruminolytic agents
Indian Journal of Otolaryngology and Head & Neck Surgery, 10/07/2009

of ceruminolytic agents, i.e 2% paradichlorobenzene, 10% sodium bicarbonate, 2.5% acetic acid and normal saline. 2% paradichlorobenzene emerged as the most superior ceruminolytic, closely followed by 10% sodium bicarbonate. 2.5% acetic acid fared moderately while normal saline emerged as the least [more...]

Sodium Bicarbonate Plus N-Acetylcysteine Prophylaxis
JACC - Journal of the American College of Cardiology: Cardiovascular Interventions, 11/20/2009

Brown JR et al. – Combination prophylaxis with NAC and NaHCO3 substantially reduced the occurrence of contrast–induced AKI overall but not dialysis–dependent renal failure. Combination prophylaxis should be incorporated for all ... ndash;risk patients (emergent cases or patients with chronic kidney disease) and should be strongly considered for all interventional radio–contrast procedures. [more...]

In vitro tests and modelization of bicarbonate kinetics and mass transfers during online hemodiafiltration
The International Journal of Artificial Organs, 10/30/2009

Morel H et al. – The data confirmed that online HDF automatically corrects acidosis without creating alkalosis when HCO3 – dialysate concentration is around 30 mmol/L [more...]

Acid-Base Balance in Peritoneal Dialysis Patients: A Stewart-Fencl Analysis
Renal Failure, 10/29/2009

Klaboch J et al. – The results suggest that the decreased bicarbonate in PD patients results from a combination of decreased sodium–chloride difference and mildly increased unmeasured anions. [more...]

Compensatory role of inducible annexin A2 for impaired biliary epithelial anion-exchange activity of inflammatory cholangiopathy
Laboratory Investigation, 10/19/2009

Inducible ANXA2 expression in cholangiocytes may play a compensatory role for the impaired AE activity of cholangiocytes in PBC in terms of bicarbonate–rich ductular secretion and bile formation through modulation of the PKC activity. [more...]