Update in Primary Aldosteronism
Journal of Clinical Endocrinology and Metabolism, 09/11/2009
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Stowasser M – It is now widely recognized that primary aldosteronism (PA) is much more common than previously thought, accounting for up to 5–10% of hypertensives, and that aldosterone excess has adverse cardiovascular consequences that go above and beyond ... These findings have precipitated a marked resurgence of research activity, most of which has supported the concept that PA plays an important role in cardiovascular disease states and should be systematically sought and specifically treated.
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Systematic Review: Diagnostic Procedures to Differentiate Unilateral From Bilateral Adrenal Abnormality in Primary Aldosteronism
Annals of Internal Medicine, 09/02/2009
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Kempers MJE et al. – Primary aldosteronism can involve 1 or both adrenal glands. Surgery is indicated only for unilateral disease. Experts prefer adrenal vein ... unilateral disease in 19.1%, and removal of the wrong adrenal in 3.9%. Relying only on CT/MRI may lead to inappropriate treatment of patients with primary aldosteronism.
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Case detection, diagnosis, and treatment of patients with primary aldosteronism: an Endocrine Society clinical practice guideline
European Journal of Endocrinology, 10/14/2009
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Funder J et al. – Systematic reviews of available evidence were used to formulate the key treatment and prevention recommendations. The authors used the Grading ... group criteria to describe both the quality of evidence and the strength of recommendations.
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Impact of Accessory Hepatic Veins on Adrenal Vein Sampling for Identification of Surgically Curable Primary Aldosteronism
Hypertension, 08/21/2009
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Miotto D et al. – In the presence of this anatomic variation, superselective catheterization of the right adrenal vein should be undertaken to determine the
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131I-6 beta-Iodomethyl-19-Norcholesterol SPECT/CT for Primary Aldosteronism Patients with Inconclusive Adrenal Venous Sampling and CT Results
The Journal of Nuclear Medicine, 09/24/2009
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Yen RF et al. – NP–59 SPECT/CT is an effective imaging tool for differentiating APA from IAH in PA patients whose CT and AVS results are
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