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See Latest ArticlesZidovudine/lamivudine contributes to insulin resistance within 3 months of starting combination antiretroviral therapy
AIDS, 01/08/08
Blumer R et al. - Treatment for 3 months with a NRTI-containing, but not a NRTI-sparing, regimen resulted in a 25% decrease in insulin-mediated glucose disposal and a 22% increase in fasting lipolysis. In the absence of discernable changes in body composition, NRTI may directly affect glucose metabolism, the mechanism by which remains to be elucidated
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